Choosing the Right Pharmaceutical Mixer

Introduction

Does your pharmaceutical manufacturing process call for mixing or agitation? Agitation is commonly achieved through the use of bottom-mounted magnetic or top-mounted gear-driven mixers. While mixing may just be one component of a large-scale project, the type of mixer you choose will impact your entire process. 

Mixers can be used to keep a product homogeneous, enhance heat or mass transfers, or promote chemical and biological reactions. Many common mixing processes are used in the pharmaceutical industry, and choosing the right mixer is highly dependent upon your agitation needs. Below, we have outlined a few considerations that will help ensure you are choosing the best mixer for your project.

1. Consider Your Fluid

First, you must understand the fluid being mixed. If it is just one product in the vessel, the viscosity is the main consideration in achieving the proper agitation for your process. With two or more fluids in your vessel, miscibility and aggregation will determine which mixing process you will utilize. The products' behavior and shear sensitivity will also help decide the agitation intensity level needed. In general, top or center-mounted mixers are better suited for products that require aggressive or rapid blending. Meanwhile, bottom-mounted magnetic mixers are good for easy, gentle movement of product in your vessel.

2. Understand Your Flow Pattern

The design of your tank also plays a crucial role in your mixing process. The shape of your tank and your agitator's position will define the mixture's flow pattern. Magnetic mixers are placed at the bottom of the tank, creating a top-to-bottom vortex. In contrast, top-mounted mixers can be located in the center or offset, allowing for more flexibility in the flow pattern.

3. Know Your Deadline

Getting your pharmaceuticals to market can be a lengthy process with research, testing, and regulations, and purchasing custom equipment can have a big impact on this schedule. Finding an equipment supplier that can provide everything from mixers to tanks and skids is important. A total solution provider can design all your equipment needs, so you don't need to work with multiple suppliers. This will result in you getting your equipment faster.